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Distinct activation modes of the Relaxin Family Peptide Receptor 2 in response to insulin-like peptide 3 and relaxin
Relaxin family peptide receptor 2 (RXFP2) is a GPCR known for its role in reproductive function. It is structurally related to the human relaxin receptor RXFP1 and can be activated by human gene-2 (H2) relaxin as well as its cognate ligand insulin-like peptide 3 (INSL3). Both receptors possess an N-...
Autores principales: | Bruell, Shoni, Sethi, Ashish, Smith, Nicholas, Scott, Daniel J., Hossain, Mohammed Akhter, Wu, Qing-Ping, Guo, Zhan-Yun, Petrie, Emma J., Gooley, Paul R., Bathgate, Ross A. D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468325/ https://www.ncbi.nlm.nih.gov/pubmed/28607406 http://dx.doi.org/10.1038/s41598-017-03638-4 |
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