Cargando…

Revisiting the Role of Interleukin-1 Pathway in Osteoarthritis: Interleukin-1α and -1β, and NLRP3 Inflammasome Are Not Involved in the Pathological Features of the Murine Menisectomy Model of Osteoarthritis

Background: Innate immune response components such as toll-like receptors (TLRs) and NLRP3-inflammasome act in concert to increase IL-1α/β secretion by synovial macrophages. Previous results suggest that IL-1α/β could be an important mediator involved in the pathogenesis of osteoarthritis (OA). Obje...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nasi, Sonia, Ea, Hang-Korng, So, Alexander, Busso, Nathalie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468399/ https://www.ncbi.nlm.nih.gov/pubmed/28659793 http://dx.doi.org/10.3389/fphar.2017.00282

Ejemplares similares

Sodium Thiosulfate Prevents Chondrocyte Mineralization and Reduces the Severity of Murine Osteoarthritis
por: Nasi, Sonia, et al.
Publicado: (2016)

Interleukin-1 and the NLRP3 Inflammasome in Pericardial Disease
por: Vecchié, Alessandra, et al.
Publicado: (2021)

Betulinic Acid Attenuates Osteoarthritis via Limiting NLRP3 Inflammasome Activation to Decrease Interleukin-1β Maturation and Secretion
por: Liu, Bo, et al.
Publicado: (2023)

The NLRP3 inflammasome – interleukin 1β axis in uveal melanoma
por: Correa, Victor S. M. C., et al.
Publicado: (2023)

Extract From Plectranthus amboinicus Inhibit Maturation and Release of Interleukin 1β Through Inhibition of NF-κB Nuclear Translocation and NLRP3 Inflammasome Activation
por: Leu, Wohn-Jenn, et al.
Publicado: (2019)

Interleukin-1 and the NLRP3 inflammasome in COVID-19: Pathogenetic and therapeutic implications
por: Potere, Nicola, et al.
Publicado: (2022)

Vanillic Acid Reduces Pain-Related Behavior in Knee Osteoarthritis Rats Through the Inhibition of NLRP3 Inflammasome-Related Synovitis
por: Ma, Zhenyuan, et al.
Publicado: (2021)

NLRP3 inflammasome is responsible for Hantavirus inducing interleukin-1β in THP-1 cells
por: Ye, Wei, et al.
Publicado: (2019)

Interleukin-1-Interleukin-17 Signaling Axis Induces Cartilage Destruction and Promotes Experimental Osteoarthritis
por: Na, Hyun Sik, et al.
Publicado: (2020)

Revisiting the origin of interleukin 1 in anamniotes and sub-functionalization of interleukin 1 in amniotes
por: Hasel de Carvalho, Eva, et al.
Publicado: (2022)

SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation
por: Liu, Jian-Wei, et al.
Publicado: (2021)

Corrigendum: Interleukin-1-Interleukin-17 Signaling Axis Induces Cartilage Destruction and Promotes Experimental Osteoarthritis
por: Na, Hyun Sik, et al.
Publicado: (2020)

CD11b Signaling Prevents Chondrocyte Mineralization and Attenuates the Severity of Osteoarthritis
por: Ehirchiou, Driss, et al.
Publicado: (2020)

Rescued Chondrogenesis of Mesenchymal Stem Cells under Interleukin 1 Challenge by Foamyviral Interleukin 1 Receptor Antagonist Gene Transfer
por: Armbruster, Nicole, et al.
Publicado: (2017)

Polyene Macrolide Antifungal Drugs Trigger Interleukin-1β Secretion by Activating the NLRP3 Inflammasome
por: Darisipudi, Murthy Narayana, et al.
Publicado: (2011)

Neurodegenerative Disease and the NLRP3 Inflammasome
por: Holbrook, Jonathan A., et al.
Publicado: (2021)

Mitochondrial uncoupling protein 1 antagonizes atherosclerosis by blocking NLRP3 inflammasome–dependent interleukin-1β production
por: Gu, Ping, et al.
Publicado: (2021)

Inhibition of Nrf2/HO-1 signaling leads to increased activation of the NLRP3 inflammasome in osteoarthritis
por: Chen, Zhuming, et al.
Publicado: (2019)

Hepatic inflammasome activation as origin of Interleukin-1α and Interleukin-1β in liver cirrhosis
por: Praktiknjo, Michael, et al.
Publicado: (2021)

Ketogenic diet ameliorates inflammation by inhibiting the NLRP3 inflammasome in osteoarthritis
por: Kong, Ganggang, et al.
Publicado: (2022)

Revisiting spatial distribution and biochemical composition of calcium-containing crystals in human osteoarthritic articular cartilage
por: Nguyen, Christelle, et al.
Publicado: (2013)

A roadmap to target interleukin-6 in osteoarthritis
por: Wiegertjes, Renske, et al.
Publicado: (2020)

Interleukin-6 and ratio of plasma interleukin-6/interleukin-10 as risk factors of symptomatic lumbar osteoarthritis
por: Suyasa, I Ketut, et al.
Publicado: (2017)

Dental Calculus Stimulates Interleukin-1β Secretion by Activating NLRP3 Inflammasome in Human and Mouse Phagocytes
por: Montenegro Raudales, Jorge Luis, et al.
Publicado: (2016)

The role of NLRP3 inflammasome in hepatocellular carcinoma
por: Zhao, Huijie, et al.
Publicado: (2023)

Effect of interleukin-31 on septic shock through regulating inflammasomes and interleukin-1β
por: Gu, Xuyun, et al.
Publicado: (2018)

Targeting Inflammatory Pathways in Cardiovascular Disease: The Inflammasome, Interleukin-1, Interleukin-6 and Beyond
por: Libby, Peter
Publicado: (2021)

Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation
por: Gregersen, Ida, et al.
Publicado: (2017)

NLRP3 inflammasome triggers interleukin‐37 release from human monocytes
por: Gritsenko, Anna, et al.
Publicado: (2022)

The Role of Interleukin-17A and NLRP3 Inflammasome in the Pathogenesis of Graves’ Ophthalmopathy
por: Lin, Chih-Chung, et al.
Publicado: (2023)

Agnuside Alleviates Synovitis and Fibrosis in Knee Osteoarthritis through the Inhibition of HIF-1α and NLRP3 Inflammasome
por: Zhang, Li, et al.
Publicado: (2021)

The protective role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (H(2)S) pathway against experimental osteoarthritis
por: Nasi, Sonia, et al.
Publicado: (2020)

Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation
por: Ives, Annette, et al.
Publicado: (2015)

Inflammasome signaling and regulation of interleukin-1 family cytokines
por: Chan, Amy H., et al.
Publicado: (2019)

The P2X7 Receptor-Interleukin-1 Liaison
por: Giuliani, Anna Lisa, et al.
Publicado: (2017)

Effects of Interleukin-1β in Glycinergic Transmission at the Central Amygdala
por: Solorza, Jocelyn, et al.
Publicado: (2021)

Electroacupuncture Alleviates Osteoarthritis by Suppressing NLRP3 Inflammasome Activation in Guinea Pigs
por: Wang, Zhankui, et al.
Publicado: (2020)

Leptin and interleukin-1β levels associated with osteoarthritis in Vietnamese patients: a cross-sectional analysis
por: Mai, N.T.T., et al.
Publicado: (2023)

Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations
por: Attur, Mukundan, et al.
Publicado: (2009)

Potential Influence of Interleukin-1 Receptor Antagonist Gene Polymorphism on Knee Osteoarthritis Risk
por: Swellam, Menha, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_b22evmqihi0ed3i40oua9lahlc