Cargando…
Behavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models
Parkinson's disease (PD) is a neurodegenerative disorder with symptoms that progressively worsen with age. Pathologically, PD is characterized by the aggregation of α-synuclein in cells of the substantia nigra in the brain and loss of dopaminergic neurons. This pathology is associated with impa...
Autores principales: | Maulik, Malabika, Mitra, Swarup, Bult-Ito, Abel, Taylor, Barbara E., Vayndorf, Elena M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468440/ https://www.ncbi.nlm.nih.gov/pubmed/28659967 http://dx.doi.org/10.3389/fgene.2017.00077 |
Ejemplares similares
-
Genetic Silencing of Fatty Acid Desaturases Modulates α-Synuclein Toxicity and Neuronal Loss in Parkinson-Like Models of C. elegans
por: Maulik, Malabika, et al.
Publicado: (2019) -
Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans
por: Maulik, Malabika, et al.
Publicado: (2018) -
Allosterism of Nicotinic Acetylcholine Receptors: Therapeutic Potential for Neuroinflammation Underlying Brain Trauma and Degenerative Disorders
por: Mitra, Swarup, et al.
Publicado: (2020) -
Bidirectional Behavioral Selection in Mice: A Novel Pre-clinical Approach to Examining Compulsivity
por: Mitra, Swarup, et al.
Publicado: (2021) -
Insulin signaling in the aging of healthy and proteotoxically stressed mechanosensory neurons
por: Scerbak, Courtney, et al.
Publicado: (2014)