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A Mighty “Protein Extractor” of the Cell: Structure and Function of the p97/CDC48 ATPase

p97/VCP (known as Cdc48 in S. cerevisiae or TER94 in Drosophila) is one of the most abundant cytosolic ATPases. It is highly conserved from archaebacteria to eukaryotes. In conjunction with a large number of cofactors and adaptors, it couples ATP hydrolysis to segregation of polypeptides from immobi...

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Detalles Bibliográficos
Autores principales: Ye, Yihong, Tang, Wai Kwan, Zhang, Ting, Xia, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468458/
https://www.ncbi.nlm.nih.gov/pubmed/28660197
http://dx.doi.org/10.3389/fmolb.2017.00039