Cargando…
A Mighty “Protein Extractor” of the Cell: Structure and Function of the p97/CDC48 ATPase
p97/VCP (known as Cdc48 in S. cerevisiae or TER94 in Drosophila) is one of the most abundant cytosolic ATPases. It is highly conserved from archaebacteria to eukaryotes. In conjunction with a large number of cofactors and adaptors, it couples ATP hydrolysis to segregation of polypeptides from immobi...
Autores principales: | Ye, Yihong, Tang, Wai Kwan, Zhang, Ting, Xia, Di |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468458/ https://www.ncbi.nlm.nih.gov/pubmed/28660197 http://dx.doi.org/10.3389/fmolb.2017.00039 |
Ejemplares similares
-
Targeting of client proteins to the VCP/p97/Cdc48 unfolding machine
por: Meyer, Hemmo, et al.
Publicado: (2023) -
Mutations in the Human AAA(+) Chaperone p97 and Related Diseases
por: Tang, Wai Kwan, et al.
Publicado: (2016) -
Toward an understanding of the Cdc48/p97 ATPase
por: Bodnar, Nicholas, et al.
Publicado: (2017) -
The Interplay of Cofactor Interactions and Post-translational Modifications in the Regulation of the AAA+ ATPase p97
por: Hänzelmann, Petra, et al.
Publicado: (2017) -
Biological and Pathological Implications of an Alternative ATP-Powered Proteasomal Assembly With Cdc48 and the 20S Peptidase
por: Esaki, Masatoshi, et al.
Publicado: (2018)