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Corneal Collagen Crosslinking Treatment in a Case with Pneumococcal Keratitis

Bacterial keratitis is a serious ocular infectious disease that can threaten vision. The disease generally progresses rapidly and can lead to corneal scar, stromal abscess formation, perforation, and dissemination to adjacent tissues if not treated properly. Recent studies showed that corneal collag...

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Autores principales: Bozkurt Oflaz, Ayşe, Bozkurt, Banu, Kamış, Ümit, Ekinci Köktekir, Bengü
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468530/
https://www.ncbi.nlm.nih.gov/pubmed/28630792
http://dx.doi.org/10.4274/tjo.98470
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author Bozkurt Oflaz, Ayşe
Bozkurt, Banu
Kamış, Ümit
Ekinci Köktekir, Bengü
author_facet Bozkurt Oflaz, Ayşe
Bozkurt, Banu
Kamış, Ümit
Ekinci Köktekir, Bengü
author_sort Bozkurt Oflaz, Ayşe
collection PubMed
description Bacterial keratitis is a serious ocular infectious disease that can threaten vision. The disease generally progresses rapidly and can lead to corneal scar, stromal abscess formation, perforation, and dissemination to adjacent tissues if not treated properly. Recent studies showed that corneal collagen crosslinking (CCC) using ultraviolet-A/riboflavin is effective in the treatment of bacterial keratitis refractory to topical antibiotic treatment. In addition to being bactericidal, CCC also decreases risk of perforation by strengthening the corneal collagen structure. Herein, we report a male patient with Streptococcus pneumonia keratitis 6 months after a keratoplasty procedure, which did not respond to fortified topical antibiotic therapy and was treated successfully with riboflavin/ultraviolet-A CCC. His pain decreased remarkably in a few days. The corneal epithelial defect healed and infiltration regressed within 2 weeks after CCC. His vision improved significantly from hand movement to 20/400. CCC might be used as adjuvant treatment in bacterial keratitis refractory to medical treatment.
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spelling pubmed-54685302017-06-19 Corneal Collagen Crosslinking Treatment in a Case with Pneumococcal Keratitis Bozkurt Oflaz, Ayşe Bozkurt, Banu Kamış, Ümit Ekinci Köktekir, Bengü Turk J Ophthalmol Case Report Bacterial keratitis is a serious ocular infectious disease that can threaten vision. The disease generally progresses rapidly and can lead to corneal scar, stromal abscess formation, perforation, and dissemination to adjacent tissues if not treated properly. Recent studies showed that corneal collagen crosslinking (CCC) using ultraviolet-A/riboflavin is effective in the treatment of bacterial keratitis refractory to topical antibiotic treatment. In addition to being bactericidal, CCC also decreases risk of perforation by strengthening the corneal collagen structure. Herein, we report a male patient with Streptococcus pneumonia keratitis 6 months after a keratoplasty procedure, which did not respond to fortified topical antibiotic therapy and was treated successfully with riboflavin/ultraviolet-A CCC. His pain decreased remarkably in a few days. The corneal epithelial defect healed and infiltration regressed within 2 weeks after CCC. His vision improved significantly from hand movement to 20/400. CCC might be used as adjuvant treatment in bacterial keratitis refractory to medical treatment. Galenos Publishing 2017-06 2017-06-01 /pmc/articles/PMC5468530/ /pubmed/28630792 http://dx.doi.org/10.4274/tjo.98470 Text en © Copyright 2017 by Turkish Ophthalmological Association Turkish Journal of Ophthalmology, published by Galenos Publishing House. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bozkurt Oflaz, Ayşe
Bozkurt, Banu
Kamış, Ümit
Ekinci Köktekir, Bengü
Corneal Collagen Crosslinking Treatment in a Case with Pneumococcal Keratitis
title Corneal Collagen Crosslinking Treatment in a Case with Pneumococcal Keratitis
title_full Corneal Collagen Crosslinking Treatment in a Case with Pneumococcal Keratitis
title_fullStr Corneal Collagen Crosslinking Treatment in a Case with Pneumococcal Keratitis
title_full_unstemmed Corneal Collagen Crosslinking Treatment in a Case with Pneumococcal Keratitis
title_short Corneal Collagen Crosslinking Treatment in a Case with Pneumococcal Keratitis
title_sort corneal collagen crosslinking treatment in a case with pneumococcal keratitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468530/
https://www.ncbi.nlm.nih.gov/pubmed/28630792
http://dx.doi.org/10.4274/tjo.98470
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