UHRF1 is required for basal stem cell proliferation in response to airway injury

Cellular senescence is a cell fate characterized by an irreversible cell cycle arrest, but the molecular mechanism underlying this senescence hallmark remains poorly understood. Through an unbiased search for novel senescence regulators in airway basal cells, we discovered that the epigenetic regula...

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Detalles Bibliográficos
Autores principales: Xiang, Handan, Yuan, Lifeng, Gao, Xia, Alexander, Peter B, Lopez, Omar, Lau, Calvin, Ding, Yi, Chong, Mengyang, Sun, Tao, Chen, Rui, Liu, Si-Qi, Wu, Haiyang, Wan, Ying, Randell, Scott H, Li, Qi-Jing, Wang, Xiao-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468773/
https://www.ncbi.nlm.nih.gov/pubmed/28626588
http://dx.doi.org/10.1038/celldisc.2017.19

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