Hyperlipidemic microenvironment conditionates damage mechanisms in human chondrocytes by oxidative stress

BACKGROUND: Currently, two pathogenic pathways describe the role of obesity in osteoarthritis (OA); one through biomechanical stress, and the other by the contribution of systemic inflammation. The aim of this study was to evaluate the effect of free fatty acids (FFA) in human chondrocytes (HC) expr...

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Detalles Bibliográficos
Autores principales: Medina-Luna, Daniel, Santamaría-Olmedo, Mónica Guadalupe, Zamudio-Cuevas, Yessica, Martínez-Flores, Karina, Fernández-Torres, Javier, Martínez-Nava, Gabriela Angélica, Clavijo-Cornejo, Denise, Hernández-Díaz, Cristina, Olivos-Meza, Anell, Gomez-Quiroz, Luis Enrique, Gutiérrez-Ruiz, María Concepción, Pineda, Carlos, Blanco, Francisco, Reginato, Anthony M., López-Reyes, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468939/
https://www.ncbi.nlm.nih.gov/pubmed/28606092
http://dx.doi.org/10.1186/s12944-017-0510-x

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