Microglia limit the expansion of β-amyloid plaques in a mouse model of Alzheimer’s disease

BACKGROUND: Microglia are known as resident immune cells in the brain. β-amyloid (Aβ) plaques in the brain of Alzheimer’s disease (AD) are surrounded by microglia, but whether and how microglia affect the formation and maintenance of plaques remains controversial. METHODS: We depleted microglia by i...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Ruohe, Hu, Wanling, Tsai, Julia, Li, Wei, Gan, Wen-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468952/
https://www.ncbi.nlm.nih.gov/pubmed/28606182
http://dx.doi.org/10.1186/s13024-017-0188-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468952/
https://www.ncbi.nlm.nih.gov/pubmed/28606182
http://dx.doi.org/10.1186/s13024-017-0188-6

Ejemplares similares