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Microglia limit the expansion of β-amyloid plaques in a mouse model of Alzheimer’s disease

BACKGROUND: Microglia are known as resident immune cells in the brain. β-amyloid (Aβ) plaques in the brain of Alzheimer’s disease (AD) are surrounded by microglia, but whether and how microglia affect the formation and maintenance of plaques remains controversial. METHODS: We depleted microglia by i...

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Detalles Bibliográficos
Autores principales:	Zhao, Ruohe, Hu, Wanling, Tsai, Julia, Li, Wei, Gan, Wen-Biao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468952/ https://www.ncbi.nlm.nih.gov/pubmed/28606182 http://dx.doi.org/10.1186/s13024-017-0188-6

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