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Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase

BACKGROUND: Aspartate, which is converted from oxaloacetate (OAA) by aspartate aminotransferase, is considered an important precursor for purine salvage and pyrimidine de novo biosynthesis, and is thus indispensable for the growth of Plasmodium parasites at the asexual blood stages. OAA can be produ...

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Detalles Bibliográficos
Autores principales:	Niikura, Mamoru, Komatsuya, Keisuke, Inoue, Shin-Ichi, Matsuda, Risa, Asahi, Hiroko, Inaoka, Daniel Ken, Kita, Kiyoshi, Kobayashi, Fumie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469008/ https://www.ncbi.nlm.nih.gov/pubmed/28606087 http://dx.doi.org/10.1186/s12936-017-1898-5

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