Cargando…
Obesity Accelerates Alzheimer-Related Pathology in APOE4 but not APOE3 Mice
Alzheimer’s disease (AD) risk is modified by both genetic and environmental risk factors, which are believed to interact to cooperatively modify pathogenesis. Although numerous genetic and environmental risk factors for AD have been identified, relatively little is known about potential gene-environ...
Autores principales: | Moser, V. Alexandra, Pike, Christian J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469027/ https://www.ncbi.nlm.nih.gov/pubmed/28612048 http://dx.doi.org/10.1523/ENEURO.0077-17.2017 |
Ejemplares similares
-
Microglial transcription profiles in mouse and human are driven by APOE4 and sex
por: Moser, V. Alexandra, et al.
Publicado: (2021) -
APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer’s disease pathology and brain diseases
por: Fernández-Calle, Rosalía, et al.
Publicado: (2022) -
Blocking the apoE/Aβ interaction
ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement
Alzheimer model mice
por: Pankiewicz, Joanna E, et al.
Publicado: (2014) -
CSF biomarkers for Alzheimer's pathology and the effect size of APOE ɛ4
por: Andreasson, U, et al.
Publicado: (2014) -
ApoE Regulates the Development of Adult Newborn Hippocampal Neurons
por: Tensaouti, Yacine, et al.
Publicado: (2018)