Recapitulating the Micromechanical Behavior of Tension and Shear in a Biomimetic Hydrogel for Controlling Tenocyte Response

A fiber composite system is presented which recapitulates the fiber‐composite‐like nature of tissues and generates similar modes of shear and tension. The shear/tension ratio can be customized during composite manufacture and incorporates viable cells. The system is a valuable tool for mechanotransd...

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Detalles Bibliográficos
Autores principales: Patel, Dharmesh, Sharma, Sadhana, Bryant, Stephanie J., Screen, Hazel R. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469035/
https://www.ncbi.nlm.nih.gov/pubmed/28026126
http://dx.doi.org/10.1002/adhm.201601095
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author Patel, Dharmesh
Sharma, Sadhana
Bryant, Stephanie J.
Screen, Hazel R. C.
author_facet Patel, Dharmesh
Sharma, Sadhana
Bryant, Stephanie J.
Screen, Hazel R. C.
author_sort Patel, Dharmesh
collection PubMed
description A fiber composite system is presented which recapitulates the fiber‐composite‐like nature of tissues and generates similar modes of shear and tension. The shear/tension ratio can be customized during composite manufacture and incorporates viable cells. The system is a valuable tool for mechanotransduction research, providing a platform with physiologically relevant conditions for investigating cell behavior in different tissue types. [Image: see text]
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spelling pubmed-54690352018-02-01 Recapitulating the Micromechanical Behavior of Tension and Shear in a Biomimetic Hydrogel for Controlling Tenocyte Response Patel, Dharmesh Sharma, Sadhana Bryant, Stephanie J. Screen, Hazel R. C. Adv Healthc Mater Communications A fiber composite system is presented which recapitulates the fiber‐composite‐like nature of tissues and generates similar modes of shear and tension. The shear/tension ratio can be customized during composite manufacture and incorporates viable cells. The system is a valuable tool for mechanotransduction research, providing a platform with physiologically relevant conditions for investigating cell behavior in different tissue types. [Image: see text] John Wiley and Sons Inc. 2016-12-27 2017-02-22 /pmc/articles/PMC5469035/ /pubmed/28026126 http://dx.doi.org/10.1002/adhm.201601095 Text en © 2016 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Communications
Patel, Dharmesh
Sharma, Sadhana
Bryant, Stephanie J.
Screen, Hazel R. C.
Recapitulating the Micromechanical Behavior of Tension and Shear in a Biomimetic Hydrogel for Controlling Tenocyte Response
title Recapitulating the Micromechanical Behavior of Tension and Shear in a Biomimetic Hydrogel for Controlling Tenocyte Response
title_full Recapitulating the Micromechanical Behavior of Tension and Shear in a Biomimetic Hydrogel for Controlling Tenocyte Response
title_fullStr Recapitulating the Micromechanical Behavior of Tension and Shear in a Biomimetic Hydrogel for Controlling Tenocyte Response
title_full_unstemmed Recapitulating the Micromechanical Behavior of Tension and Shear in a Biomimetic Hydrogel for Controlling Tenocyte Response
title_short Recapitulating the Micromechanical Behavior of Tension and Shear in a Biomimetic Hydrogel for Controlling Tenocyte Response
title_sort recapitulating the micromechanical behavior of tension and shear in a biomimetic hydrogel for controlling tenocyte response
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469035/
https://www.ncbi.nlm.nih.gov/pubmed/28026126
http://dx.doi.org/10.1002/adhm.201601095
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AT bryantstephaniej recapitulatingthemicromechanicalbehavioroftensionandshearinabiomimetichydrogelforcontrollingtenocyteresponse
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