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Antiangiogenic agents targeting different angiogenic pathways have opposite effects on tumor hypoxia in R-18 human melanoma xenografts
BACKGROUND: Studies comparing the effect of antiangiogenic agents targeting different angiogenic pathways are sparse. The purpose of this study was to compare the effect of properdistatin and sunitinib treatment in a preclinical model of malignant melanoma. Properdistatin is a small peptide derived...
Autores principales: | Gaustad, Jon-Vidar, Simonsen, Trude G., Andersen, Lise Mari K., Rofstad, Einar K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469039/ https://www.ncbi.nlm.nih.gov/pubmed/28606060 http://dx.doi.org/10.1186/s12885-017-3404-4 |
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