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Inhibition of 5-lipoxygenase by zileuton in a rat model of myocardial infarction

OBJECTIVE: The goal of the present study was to investigate the effects of 5-lipoxygenase (5-LOX) inhibition, alone and with cyclooxygenase (COX) inhibitors, on inflammatory parameters and apoptosis in ischemia/reperfusion (I/R)-induced myocardial damage in rats. For this purpose, zileuton, a select...

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Detalles Bibliográficos
Autores principales: Abueid, Leyla, Uslu, Ünal, Cumbul, Alev, Öğünç, Ayliz Velioğlu, Ercan, Feriha, Alican, İnci
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469106/
https://www.ncbi.nlm.nih.gov/pubmed/27849187
http://dx.doi.org/10.14744/AnatolJCardiol.2016.7248