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Variable-order sequence modeling improves bacterial strain discrimination for Ion Torrent DNA reads
BACKGROUND: Genome sequencing provides a powerful tool for pathogen detection and can help resolve outbreaks that pose public safety and health risks. Mapping of DNA reads to genomes plays a fundamental role in this approach, where accurate alignment and classification of sequencing data is crucial....
Autores principales: | Poulsen, Thomas M., Frith, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469136/ https://www.ncbi.nlm.nih.gov/pubmed/28606054 http://dx.doi.org/10.1186/s12859-017-1710-0 |
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