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Variable-order sequence modeling improves bacterial strain discrimination for Ion Torrent DNA reads

BACKGROUND: Genome sequencing provides a powerful tool for pathogen detection and can help resolve outbreaks that pose public safety and health risks. Mapping of DNA reads to genomes plays a fundamental role in this approach, where accurate alignment and classification of sequencing data is crucial....

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Detalles Bibliográficos
Autores principales: Poulsen, Thomas M., Frith, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469136/
https://www.ncbi.nlm.nih.gov/pubmed/28606054
http://dx.doi.org/10.1186/s12859-017-1710-0

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