Choosing the target difference (‘effect size’) for a randomised controlled trial - DELTA(2) guidance protocol

BACKGROUND: A key step in the design of a randomised controlled trial (RCT) is the estimation of the number of participants needed. By far the most common approach is to specify a target difference and then estimate the corresponding sample size; this sample size is chosen to provide reassurance tha...

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Detalles Bibliográficos
Autores principales: Cook, Jonathan A., Julious, Steven A., Sones, William, Rothwell, Joanne C., Ramsay, Craig R., Hampson, Lisa V., Emsley, Richard, Walters, Stephen J., Hewitt, Catherine, Bland, Martin, Fergusson, Dean A., Berlin, Jesse A., Altman, Doug, Vale, Luke D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469157/
https://www.ncbi.nlm.nih.gov/pubmed/28606102
http://dx.doi.org/10.1186/s13063-017-1969-5

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