Effect of lithium on ventricular remodelling in infarcted rats via the Akt/mTOR signalling pathways

Activation of phosphoinositide 3-kinase (PI3K)/Akt signalling is the molecular pathway driving physiological hypertrophy. As lithium, a PI3K agonist, is highly toxic at regular doses, we assessed the effect of lithium at a lower dose on ventricular hypertrophy after myocardial infarction (MI). Male...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Tsung-Ming, Lin, Shinn-Zong, Chang, Nen-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469250/
https://www.ncbi.nlm.nih.gov/pubmed/28115595
http://dx.doi.org/10.1042/BSR20160257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469250/
https://www.ncbi.nlm.nih.gov/pubmed/28115595
http://dx.doi.org/10.1042/BSR20160257

Ejemplares similares