CAF-derived HGF promotes cell proliferation and drug resistance by up-regulating the c-Met/PI3K/Akt and GRP78 signalling in ovarian cancer cells

The tumour microenvironment is a highly heterogeneous entity that plays crucial roles in cancer progression. As the most prominent stromal cell types, cancer-associated fibroblasts (CAFs) produce a variety of factors into the tumour microenvironment. In the present study, we firstly isolated CAFs fr...

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Detalles Bibliográficos
Autores principales: Deying, Wei, Feng, Geng, Shumei, Liang, Hui, Zhao, Ming, Liu, Hongqing, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469328/
https://www.ncbi.nlm.nih.gov/pubmed/28258248
http://dx.doi.org/10.1042/BSR20160470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469328/
https://www.ncbi.nlm.nih.gov/pubmed/28258248
http://dx.doi.org/10.1042/BSR20160470

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