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CAF-derived HGF promotes cell proliferation and drug resistance by up-regulating the c-Met/PI3K/Akt and GRP78 signalling in ovarian cancer cells
The tumour microenvironment is a highly heterogeneous entity that plays crucial roles in cancer progression. As the most prominent stromal cell types, cancer-associated fibroblasts (CAFs) produce a variety of factors into the tumour microenvironment. In the present study, we firstly isolated CAFs fr...
Autores principales: | Deying, Wei, Feng, Geng, Shumei, Liang, Hui, Zhao, Ming, Liu, Hongqing, Wang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469328/ https://www.ncbi.nlm.nih.gov/pubmed/28258248 http://dx.doi.org/10.1042/BSR20160470 |
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