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Quickly identifying identical and closely related subjects in large databases using genotype data

Genome-wide association studies (GWAS) usually rely on the assumption that different samples are not from closely related individuals. Detection of duplicates and close relatives becomes more difficult both statistically and computationally when one wants to combine datasets that may have been genot...

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Detalles Bibliográficos
Autores principales: Jin, Yumi, Schäffer, Alejandro A., Sherry, Stephen T., Feolo, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469481/
https://www.ncbi.nlm.nih.gov/pubmed/28609482
http://dx.doi.org/10.1371/journal.pone.0179106

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