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On the effects of alternative optima in context-specific metabolic model predictions
The integration of experimental data into genome-scale metabolic models can greatly improve flux predictions. This is achieved by restricting predictions to a more realistic context-specific domain, like a particular cell or tissue type. Several computational approaches to integrate data have been p...
Autores principales: | Robaina-Estévez, Semidán, Nikoloski, Zoran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469500/ https://www.ncbi.nlm.nih.gov/pubmed/28557990 http://dx.doi.org/10.1371/journal.pcbi.1005568 |
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