The cell non-autonomous function of ATG-18 is essential for neuroendocrine regulation of Caenorhabditis elegans lifespan

Dietary restriction (DR) and reduced insulin growth factor (IGF) signaling extend lifespan in Caenorhabditis elegans and other eukaryotic organisms. Autophagy, an evolutionarily conserved lysosomal degradation pathway, has emerged as a central pathway regulated by various longevity signals including...

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Detalles Bibliográficos
Autores principales: Minnerly, Justin, Zhang, Jiuli, Parker, Thomas, Kaul, Tiffany, Jia, Kailiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469504/
https://www.ncbi.nlm.nih.gov/pubmed/28557996
http://dx.doi.org/10.1371/journal.pgen.1006764

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