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Novel mRNA-specific effects of ribosome drop-off on translation rate and polysome profile

The well established phenomenon of ribosome drop-off plays crucial roles in translational accuracy and nutrient starvation responses during protein translation. When cells are under stress conditions, such as amino acid starvation or aminoacyl-tRNA depletion due to a high level of recombinant protei...

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Detalles Bibliográficos
Autores principales: Bonnin, Pierre, Kern, Norbert, Young, Neil T., Stansfield, Ian, Romano, M. Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469512/
https://www.ncbi.nlm.nih.gov/pubmed/28558053
http://dx.doi.org/10.1371/journal.pcbi.1005555