Deletion of inositol-requiring enzyme-1α in podocytes disrupts glomerular capillary integrity and autophagy

Inositol-requiring enzyme-1α (IRE1α) is an endoplasmic reticulum (ER)–transmembrane endoribonuclease kinase that plays an essential function in extraembryonic tissues during normal development and is activated during ER stress. To address the functional role of IRE1α in glomerular podocytes, we prod...

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Detalles Bibliográficos
Autores principales: Kaufman, Daniel Robert, Papillon, Joan, Larose, Louise, Iwawaki, Takao, Cybulsky, Andrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469607/
https://www.ncbi.nlm.nih.gov/pubmed/28428258
http://dx.doi.org/10.1091/mbc.E16-12-0828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469607/
https://www.ncbi.nlm.nih.gov/pubmed/28428258
http://dx.doi.org/10.1091/mbc.E16-12-0828

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