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Interaction of PKR with single-stranded RNA

Although the antiviral kinase PKR was originally characterized as a double-stranded RNA activated enzyme it can be stimulated by RNAs containing limited secondary structure. Single-stranded regions in such RNAs contribute to binding and activation but the mechanism is not understood. Here, we demons...

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Detalles Bibliográficos
Autores principales:	Mayo, Christopher B., Cole, James L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469796/ https://www.ncbi.nlm.nih.gov/pubmed/28611419 http://dx.doi.org/10.1038/s41598-017-03047-7

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