Nuclear TRADD prevents DNA damage-mediated death by facilitating non-homologous end-joining repair

TNF receptor-associated death domain (TRADD) is an essential mediator of TNF receptor signaling, and serves as an adaptor to recruit other effectors. TRADD has been shown to cycle between the cytoplasm and nucleus due to its nuclear localization (NLS) and export sequences (NES). However, the underly...

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Detalles Bibliográficos
Autores principales: Koo, Gi-Bang, Ji, Jae-Hoon, Cho, Hyeseong, Morgan, Michael J., Kim, You-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469829/
https://www.ncbi.nlm.nih.gov/pubmed/28611389
http://dx.doi.org/10.1038/s41598-017-03211-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469829/
https://www.ncbi.nlm.nih.gov/pubmed/28611389
http://dx.doi.org/10.1038/s41598-017-03211-z

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