Fibroblasts derived from oesophageal adenocarcinoma differ in DNA methylation profile from normal oesophageal fibroblasts

Oesophageal adenocarcinoma (OAC) is increasing in incidence and has a poor prognosis. Tumour derived fibroblasts (TDFs) differ functionally from normal fibroblasts (NDFs), and play a pivotal role in cancer. Many of the differences persist through subculture. We measured the DNA methylation profiles...

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Detalles Bibliográficos
Autores principales: Smith, Eric, Palethorpe, Helen M., Hayden, Annette L., Young, Joanne P., Underwood, Timothy J., Drew, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469830/
https://www.ncbi.nlm.nih.gov/pubmed/28611465
http://dx.doi.org/10.1038/s41598-017-03501-6

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