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Understanding Hematopoietic Stem Cell Development through Functional Correlation of Their Proliferative Status with the Intra-aortic Cluster Architecture
During development, hematopoietic stem cells (HSCs) emerge in the aorta-gonad-mesonephros (AGM) region through a process of multi-step maturation and expansion. While proliferation of adult HSCs is implicated in the balance between self-renewal and differentiation, very little is known about the pro...
Autores principales: | Batsivari, Antoniana, Rybtsov, Stanislav, Souilhol, Celine, Binagui-Casas, Anahi, Hills, David, Zhao, Suling, Travers, Paul, Medvinsky, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469869/ https://www.ncbi.nlm.nih.gov/pubmed/28479304 http://dx.doi.org/10.1016/j.stemcr.2017.04.003 |
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