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Immune Checkpoint Function of CD85j in CD8 T Cell Differentiation and Aging

Aging is associated with an increased susceptibility to infection and a failure to control latent viruses thought to be driven, at least in part, by alterations in CD8 T cell function. The aging T cell repertoire is characterized by an accumulation of effector CD8 T cells, many of which express the...

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Detalles Bibliográficos
Autores principales:	Gustafson, Claire E., Qi, Qian, Hutter-Saunders, Jessica, Gupta, Sheena, Jadhav, Rohit, Newell, Evan, Maecker, Holden, Weyand, Cornelia M., Goronzy, Jörg J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469909/ https://www.ncbi.nlm.nih.gov/pubmed/28659925 http://dx.doi.org/10.3389/fimmu.2017.00692

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