Cargando…
Functional and Homeostatic Impact of Age-Related Changes in Lymph Node Stroma
Adults over 65 years of age are more vulnerable to infectious disease and show poor responses to vaccination relative to those under 50. A complex set of age-related changes in the immune system is believed to be largely responsible for these defects. These changes, collectively termed immune senesc...
Autores principales: | Thompson, Heather L., Smithey, Megan J., Surh, Charles D., Nikolich-Žugich, Janko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469916/ https://www.ncbi.nlm.nih.gov/pubmed/28659930 http://dx.doi.org/10.3389/fimmu.2017.00706 |
Ejemplares similares
-
Defective Transcriptional Programming of Effector CD8 T Cells in Aged Mice Is Cell-Extrinsic and Can Be Corrected by Administration of IL-12 and IL-18
por: Jergović, Mladen, et al.
Publicado: (2019) -
Corrigendum: Defective Transcriptional Programming of Effector CD8 T Cells in Aged Mice Is Cell-Extrinsic and Can Be Corrected by Administration of IL-12 and IL-18
por: Jergović, Mladen, et al.
Publicado: (2020) -
Lymph nodes as barriers to T‐cell rejuvenation in aging mice and nonhuman primates
por: Thompson, Heather L., et al.
Publicado: (2018) -
Age-associated alterations in CD8α+ dendritic cells impair CD8 T-cell expansion in response to an intracellular bacterium
por: Li, Gang, et al.
Publicado: (2012) -
T cell aging: naive but not young
por: Nikolich-Žugich, Janko
Publicado: (2005)