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Rapid Elimination of Blood Alcohol Using Erythrocytes: Mathematical Modeling and In Vitro Study

Erythrocytes (RBCs) loaded with alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALD) can metabolize plasma ethanol and acetaldehyde but with low efficiency. We investigated the rate-limiting factors in ethanol oxidation by these enzymes loaded into RBCs. Mathematical modeling and in vitro ex...

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Detalles Bibliográficos
Autores principales:	Alexandrovich, Yuliya G., Kosenko, Elena A., Sinauridze, Elena I., Obydennyi, Sergey I., Kireev, Igor I., Ataullakhanov, Fazoil I., Kaminsky, Yuriy G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470050/ https://www.ncbi.nlm.nih.gov/pubmed/28642875 http://dx.doi.org/10.1155/2017/5849593

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