Cargando…
An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5
The Nucleosome Remodeling and Deacetylase (NuRD) complex is a chromatin regulatory complex that functions as a transcriptional co-repressor in metazoans. The NuRD subunit MBD3 is essential for targeting and assembly of a functional NuRD complex as well as embryonic stem cell (ESC) pluripotency. Thre...
Autores principales: | Ee, Ly-Sha, McCannell, Kurtis N., Tang, Yang, Fernandes, Nancy, Hardy, W. Rod, Green, Michael R., Chu, Feixia, Fazzio, Thomas G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470077/ https://www.ncbi.nlm.nih.gov/pubmed/28528697 http://dx.doi.org/10.1016/j.stemcr.2017.04.020 |
Ejemplares similares
-
NuRD-interacting protein ZFP296 regulates genome-wide NuRD localization and differentiation of mouse embryonic stem cells
por: Kloet, Susan L., et al.
Publicado: (2018) -
DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells
por: Hainer, Sarah J, et al.
Publicado: (2016) -
Characterization of Two Distinct Nucleosome Remodeling and Deacetylase (NuRD) Complex Assemblies in Embryonic Stem Cells
por: Bode, Daniel, et al.
Publicado: (2016) -
Mutants in the Mouse NuRD/Mi2 Component P66α Are Embryonic Lethal
por: Marino, Susan, et al.
Publicado: (2007) -
Specific NuRD components are required for fin regeneration in zebrafish
por: Pfefferli, Catherine, et al.
Publicado: (2014)