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Reprogramming of Dermal Fibroblasts into Osteo-Chondrogenic Cells with Elevated Osteogenic Potency by Defined Transcription Factors

Recent studies using defined transcription factors to convert skin fibroblasts into chondrocytes have raised the question of whether osteo-chondroprogenitors expressing SOX9 and RUNX2 could also be generated during the course of the reprogramming process. Here, we demonstrated that doxycycline-induc...

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Detalles Bibliográficos
Autores principales: Wang, Yinxiang, Wu, Ming-Hoi, Cheung, May Pui Lai, Sham, Mai Har, Akiyama, Haruhiko, Chan, Danny, Cheah, Kathryn S.E., Cheung, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470079/
https://www.ncbi.nlm.nih.gov/pubmed/28528696
http://dx.doi.org/10.1016/j.stemcr.2017.04.018