Inhibition of KLF4 by Statins Reverses Adriamycin-Induced Metastasis and Cancer Stemness in Osteosarcoma Cells

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Adriamycin-based combination chemotherapy is the standard first-line treatment for osteosarcoma, but tumor recurrence and metastasis occurs in most cases. Recent evidence suggests that microenvironmental stress such as chemotherapy can lead to the enrichment of cancer stem cells (CSCs), which result...

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Detalles Bibliográficos
Autores principales: Li, Yangling, Xian, Miao, Yang, Bo, Ying, Meidan, He, Qiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470096/
https://www.ncbi.nlm.nih.gov/pubmed/28552603
http://dx.doi.org/10.1016/j.stemcr.2017.04.025

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