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Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells

Astrocyte dysfunction and neuroinflammation are detrimental features in multiple pathologies of the CNS. Therefore, the development of methods that produce functional human astrocytes represents an advance in the study of neurological diseases. Here we report an efficient method for inflammation-res...

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Detalles Bibliográficos
Autores principales: Santos, Renata, Vadodaria, Krishna C., Jaeger, Baptiste N., Mei, Arianna, Lefcochilos-Fogelquist, Sabrina, Mendes, Ana P.D., Erikson, Galina, Shokhirev, Maxim, Randolph-Moore, Lynne, Fredlender, Callie, Dave, Sonia, Oefner, Ruth, Fitzpatrick, Conor, Pena, Monique, Barron, Jerika J., Ku, Manching, Denli, Ahmet M., Kerman, Bilal E., Charnay, Patrick, Kelsoe, John R., Marchetto, Maria C., Gage, Fred H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470172/
https://www.ncbi.nlm.nih.gov/pubmed/28591655
http://dx.doi.org/10.1016/j.stemcr.2017.05.011