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Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells

Human neural precursor cells (hNPCs) derived from pluripotent stem cells display a high propensity for neuronal differentiation, but they require long-term culturing to differentiate efficiently into astrocytes. The mechanisms underlying this biased fate specification of hNPCs remain elusive. Here,...

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Detalles Bibliográficos
Autores principales:	Yasui, Tetsuro, Uezono, Naohiro, Nakashima, Hideyuki, Noguchi, Hirofumi, Matsuda, Taito, Noda-Andoh, Tomoko, Okano, Hideyuki, Nakashima, Kinichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470174/ https://www.ncbi.nlm.nih.gov/pubmed/28591654 http://dx.doi.org/10.1016/j.stemcr.2017.05.001

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