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Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration
The loss of cone photoreceptors that mediate daylight vision represents a leading cause of blindness, for which cell replacement by transplantation offers a promising treatment strategy. Here, we characterize cone differentiation in retinas derived from mouse embryonic stem cells (mESCs). Similar to...
Autores principales: | Kruczek, Kamil, Gonzalez-Cordero, Anai, Goh, Debbie, Naeem, Arifa, Jonikas, Mindaugas, Blackford, Samuel J.I., Kloc, Magdalena, Duran, Yanai, Georgiadis, Anastasios, Sampson, Robert D., Maswood, Ryea N., Smith, Alexander J., Decembrini, Sarah, Arsenijevic, Yvan, Sowden, Jane C., Pearson, Rachael A., West, Emma L., Ali, Robin R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470175/ https://www.ncbi.nlm.nih.gov/pubmed/28552606 http://dx.doi.org/10.1016/j.stemcr.2017.04.030 |
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