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Transplantation of human bone marrow mesenchymal stromal cells reduces liver fibrosis more effectively than Wharton’s jelly mesenchymal stromal cells

BACKGROUND: Mesenchymal stromal cells (MSCs) from various tissues have shown moderate therapeutic efficacy in reversing liver fibrosis in preclinical models. Here, we compared the relative therapeutic potential of pooled, adult human bone marrow (BM)- and neonatal Wharton’s jelly (WJ)-derived MSCs t...

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Detalles Bibliográficos
Autores principales: Rengasamy, Mathiyazhagan, Singh, Gurbind, Fakharuzi, Noor Atiqah, Siddikuzzaman, Balasubramanian, Sudha, Swamynathan, Priyanka, Thej, Charan, Sasidharan, Gopinath, Gupta, Pawan Kumar, Das, Anjan Kumar, Rahman, Ahmad Zuhairi Abd, Fakiruddin, Kamal Shaik, Nian, Lim Moon, Zakaria, Zubaidah, Majumdar, Anish S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470281/
https://www.ncbi.nlm.nih.gov/pubmed/28610623
http://dx.doi.org/10.1186/s13287-017-0595-1