Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration

This perspective describes the usefulness of zebrafish as a model to study interaction of hematopoietic stem cells with the associated niche in vivo, explains how such interactions influence regeneration, migration, and clonality of HSCs, and defines their fate during differentiation.

Detalles Bibliográficos
Autores principales: Choudhuri, Avik, Fast, Eva M., Zon, Leonard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470329/
https://www.ncbi.nlm.nih.gov/pubmed/28591648
http://dx.doi.org/10.1016/j.stemcr.2017.05.018
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author Choudhuri, Avik
Fast, Eva M.
Zon, Leonard I.
author_facet Choudhuri, Avik
Fast, Eva M.
Zon, Leonard I.
author_sort Choudhuri, Avik
collection PubMed
description This perspective describes the usefulness of zebrafish as a model to study interaction of hematopoietic stem cells with the associated niche in vivo, explains how such interactions influence regeneration, migration, and clonality of HSCs, and defines their fate during differentiation.
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spelling pubmed-54703292017-06-23 Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration Choudhuri, Avik Fast, Eva M. Zon, Leonard I. Stem Cell Reports Perspective This perspective describes the usefulness of zebrafish as a model to study interaction of hematopoietic stem cells with the associated niche in vivo, explains how such interactions influence regeneration, migration, and clonality of HSCs, and defines their fate during differentiation. Elsevier 2017-06-09 /pmc/articles/PMC5470329/ /pubmed/28591648 http://dx.doi.org/10.1016/j.stemcr.2017.05.018 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Perspective
Choudhuri, Avik
Fast, Eva M.
Zon, Leonard I.
Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration
title Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration
title_full Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration
title_fullStr Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration
title_full_unstemmed Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration
title_short Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration
title_sort using zebrafish to study pathways that regulate hematopoietic stem cell self-renewal and migration
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470329/
https://www.ncbi.nlm.nih.gov/pubmed/28591648
http://dx.doi.org/10.1016/j.stemcr.2017.05.018
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