A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response

Microglia are increasingly implicated in brain pathology, particularly neurodegenerative disease, with many genes implicated in Alzheimer's, Parkinson's, and motor neuron disease expressed in microglia. There is, therefore, a need for authentic, efficient in vitro models to study human mic...

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Detalles Bibliográficos
Autores principales: Haenseler, Walther, Sansom, Stephen N., Buchrieser, Julian, Newey, Sarah E., Moore, Craig S., Nicholls, Francesca J., Chintawar, Satyan, Schnell, Christian, Antel, Jack P., Allen, Nicholas D., Cader, M. Zameel, Wade-Martins, Richard, James, William S., Cowley, Sally A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470330/
https://www.ncbi.nlm.nih.gov/pubmed/28591653
http://dx.doi.org/10.1016/j.stemcr.2017.05.017

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