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Modified Carba NP test for the detection of carbapenemase production in gram-negative rods: optimized handling of multiple samples

The modified Carba NP test presented here may be a valuable tool for laboratories interested in investigating a large number of carbapenemase-producing bacteria in a less-costly way. The test was evaluated against 48 carbapenemase-producing and carbapenemase-non-producing gram-negative bacteria. No...

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Detalles Bibliográficos
Autores principales: Campana, Eloiza H., Chuster, Stephanie G., da Silva, Isadora R., Paschoal, Raphael P., Bonelli, Raquel R., Moreira, Beatriz M., Picão, Renata C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470444/
https://www.ncbi.nlm.nih.gov/pubmed/27998674
http://dx.doi.org/10.1016/j.bjm.2016.09.015
Descripción
Sumario:The modified Carba NP test presented here may be a valuable tool for laboratories interested in investigating a large number of carbapenemase-producing bacteria in a less-costly way. The test was evaluated against 48 carbapenemase-producing and carbapenemase-non-producing gram-negative bacteria. No false–positive results were obtained, but false-negative results were observed with OXA-23- and GES-carbapenemase-producing isolates. Aeromonas sp. are not testable by Modified Carba NP.