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Malignant paratesticular mesothelioma

Mesothelioma of the tunica vaginalis testis (MTVT) is a rare tumor that usually affects patients after the sixth decade of life. Exposure to asbestos is a known risk factor. Enlargement of the scrotal volume is the most common initial clinical manifestation, and about 15% of cases present metastasis...

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Autores principales: da Fonseca, Leonardo Gomes, Marques, Daniel Fernandes, Takahashi, Tiago Kenji, Aguiar, Fernando Nalesso, Ravanini, Juliana Naves, Saragiotto, Daniel Fernandes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: São Paulo, SP: Universidade de São Paulo, Hospital Universitário 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470564/
https://www.ncbi.nlm.nih.gov/pubmed/28652992
http://dx.doi.org/10.4322/acr.2014.007
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author da Fonseca, Leonardo Gomes
Marques, Daniel Fernandes
Takahashi, Tiago Kenji
Aguiar, Fernando Nalesso
Ravanini, Juliana Naves
Saragiotto, Daniel Fernandes
author_facet da Fonseca, Leonardo Gomes
Marques, Daniel Fernandes
Takahashi, Tiago Kenji
Aguiar, Fernando Nalesso
Ravanini, Juliana Naves
Saragiotto, Daniel Fernandes
author_sort da Fonseca, Leonardo Gomes
collection PubMed
description Mesothelioma of the tunica vaginalis testis (MTVT) is a rare tumor that usually affects patients after the sixth decade of life. Exposure to asbestos is a known risk factor. Enlargement of the scrotal volume is the most common initial clinical manifestation, and about 15% of cases present metastasis at diagnosis. The treatment relies on surgical resection while the role of adjuvant chemotherapy and radiotherapy remains unclear. The prognosis for patients is generally poor, with a lethal outcome in 30% over a 24-month period. The authors report a case of a 62-year-old patient with the diagnosis of MTVT without a history of asbestos exposure. After surgical treatment, metastatic disease ensued. Chemotherapy was initiated, but could not be continued due to marked and fast clinical deterioration. The authors call attention to the difficulty of early diagnosis of MTVT due to a nonspecific clinical picture, the lack of action by the patient when the scrotal enlargement was first noticed, and the lack of tumor markers. Delayed diagnosis is definitely related to unfavorable prognosis.
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spelling pubmed-54705642017-06-26 Malignant paratesticular mesothelioma da Fonseca, Leonardo Gomes Marques, Daniel Fernandes Takahashi, Tiago Kenji Aguiar, Fernando Nalesso Ravanini, Juliana Naves Saragiotto, Daniel Fernandes Autops Case Rep Article / Clinical Case Reports Mesothelioma of the tunica vaginalis testis (MTVT) is a rare tumor that usually affects patients after the sixth decade of life. Exposure to asbestos is a known risk factor. Enlargement of the scrotal volume is the most common initial clinical manifestation, and about 15% of cases present metastasis at diagnosis. The treatment relies on surgical resection while the role of adjuvant chemotherapy and radiotherapy remains unclear. The prognosis for patients is generally poor, with a lethal outcome in 30% over a 24-month period. The authors report a case of a 62-year-old patient with the diagnosis of MTVT without a history of asbestos exposure. After surgical treatment, metastatic disease ensued. Chemotherapy was initiated, but could not be continued due to marked and fast clinical deterioration. The authors call attention to the difficulty of early diagnosis of MTVT due to a nonspecific clinical picture, the lack of action by the patient when the scrotal enlargement was first noticed, and the lack of tumor markers. Delayed diagnosis is definitely related to unfavorable prognosis. São Paulo, SP: Universidade de São Paulo, Hospital Universitário 2014-03-31 /pmc/articles/PMC5470564/ /pubmed/28652992 http://dx.doi.org/10.4322/acr.2014.007 Text en Copyright © 2014 Autopsy and Case Reports http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed of terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided article is properly cited.
spellingShingle Article / Clinical Case Reports
da Fonseca, Leonardo Gomes
Marques, Daniel Fernandes
Takahashi, Tiago Kenji
Aguiar, Fernando Nalesso
Ravanini, Juliana Naves
Saragiotto, Daniel Fernandes
Malignant paratesticular mesothelioma
title Malignant paratesticular mesothelioma
title_full Malignant paratesticular mesothelioma
title_fullStr Malignant paratesticular mesothelioma
title_full_unstemmed Malignant paratesticular mesothelioma
title_short Malignant paratesticular mesothelioma
title_sort malignant paratesticular mesothelioma
topic Article / Clinical Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470564/
https://www.ncbi.nlm.nih.gov/pubmed/28652992
http://dx.doi.org/10.4322/acr.2014.007
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