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5-Aza-2’-deoxycytidine in the medial prefrontal cortex regulates alcohol-related behavior and Ntf3-TrkC expression in rats

Recent studies have indicated that DNA methylation plays an important role in the development of alcohol abuse. 5-Aza-2’-deoxycytidine (5-Aza-dc), an inhibitor of DNA methyltransferases, was FDA approved for myelodysplastic syndrome treatment. However, it is unclear whether 5-Aza-dc is involved in a...

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Detalles Bibliográficos
Autores principales:	Qiao, Xiaomeng, Yin, Fangyuan, Ji, Yuanyuan, Li, Yunxiao, Yan, Peng, Lai, Jianghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470731/ https://www.ncbi.nlm.nih.gov/pubmed/28614398 http://dx.doi.org/10.1371/journal.pone.0179469

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