Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma

Mucosal melanomas are a rare subtype of melanoma, arising in mucosal tissues, which have a very poor prognosis due to the lack of effective targeted therapies. This study aimed to better understand the molecular landscape of these cancers and find potential new therapeutic targets. Whole-exome seque...

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Detalles Bibliográficos
Autores principales: Hintzsche, Jennifer D., Gorden, Nicholas T., Amato, Carol M., Kim, Jihye, Wuensch, Kelsey E., Robinson, Steven E., Applegate, Allison J., Couts, Kasey L., Medina, Theresa M., Wells, Keith R., Wisell, Joshua A., McCarter, Martin D., Box, Neil F., Shellman, Yiqun G., Gonzalez, Rene C., Lewis, Karl D., Tentler, John J., Tan, Aik Choon, Robinson, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
ORIGINAL ARTICLES: Basic science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470740/
https://www.ncbi.nlm.nih.gov/pubmed/28296713
http://dx.doi.org/10.1097/CMR.0000000000000345

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