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Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing

The anaphylatoxin receptor C5aR1 plays an important role not only in innate immune responses, but also in bone metabolism and fracture healing, being highly expressed on immune and bone cells, including osteoblasts and osteoclasts. C5aR1 induces osteoblast migration, cytokine generation and osteocla...

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Detalles Bibliográficos
Autores principales:	Bergdolt, Stephanie, Kovtun, Anna, Hägele, Yvonne, Liedert, Astrid, Schinke, Thorsten, Amling, Michael, Huber-Lang, Markus, Ignatius, Anita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470759/ https://www.ncbi.nlm.nih.gov/pubmed/28614388 http://dx.doi.org/10.1371/journal.pone.0179512

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