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Development of a Flow Injection Based High Frequency Dual Channel Quartz Crystal Microbalance
When the quartz crystal microbalance (QCM) is used in liquid for adsorption or desorption monitoring based bio- or chemical sensing applications, the frequency shift is not only determined by the surface mass change, but also by the change of liquid characteristics, such as density and viscosity, wh...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470812/ https://www.ncbi.nlm.nih.gov/pubmed/28509851 http://dx.doi.org/10.3390/s17051136 |
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author | Liang, Jinxing Zhang, Jing Zhou, Wenxiang Ueda, Toshitsugu |
author_facet | Liang, Jinxing Zhang, Jing Zhou, Wenxiang Ueda, Toshitsugu |
author_sort | Liang, Jinxing |
collection | PubMed |
description | When the quartz crystal microbalance (QCM) is used in liquid for adsorption or desorption monitoring based bio- or chemical sensing applications, the frequency shift is not only determined by the surface mass change, but also by the change of liquid characteristics, such as density and viscosity, which are greatly affected by the liquid environmental temperature. A monolithic dual-channel QCM is designed and fabricated by arranging two QCM resonators on one single chip for cancelling the fluctuation induced by environmental factors. In actual applications, one QCM works as a specific sensor by modifying with functional membranes and the other acts as a reference, only measuring the liquid property. The dual-channel QCM is designed with an inverted-mesa structure, aiming to realize a high frequency miniaturized chip and suppress the frequency interference between the neighbored QCM resonators. The key problem of dual-channel QCMs is the interference between two channels, which is influenced by the distance of adjacent resonators. The diameter of the reference electrode has been designed into several values in order to find the optimal parameter. Experimental results demonstrated that the two QCMs could vibrate individually and the output frequency stability and drift can be greatly improved with the aid of the reference QCM. |
format | Online Article Text |
id | pubmed-5470812 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-54708122017-06-16 Development of a Flow Injection Based High Frequency Dual Channel Quartz Crystal Microbalance Liang, Jinxing Zhang, Jing Zhou, Wenxiang Ueda, Toshitsugu Sensors (Basel) Article When the quartz crystal microbalance (QCM) is used in liquid for adsorption or desorption monitoring based bio- or chemical sensing applications, the frequency shift is not only determined by the surface mass change, but also by the change of liquid characteristics, such as density and viscosity, which are greatly affected by the liquid environmental temperature. A monolithic dual-channel QCM is designed and fabricated by arranging two QCM resonators on one single chip for cancelling the fluctuation induced by environmental factors. In actual applications, one QCM works as a specific sensor by modifying with functional membranes and the other acts as a reference, only measuring the liquid property. The dual-channel QCM is designed with an inverted-mesa structure, aiming to realize a high frequency miniaturized chip and suppress the frequency interference between the neighbored QCM resonators. The key problem of dual-channel QCMs is the interference between two channels, which is influenced by the distance of adjacent resonators. The diameter of the reference electrode has been designed into several values in order to find the optimal parameter. Experimental results demonstrated that the two QCMs could vibrate individually and the output frequency stability and drift can be greatly improved with the aid of the reference QCM. MDPI 2017-05-16 /pmc/articles/PMC5470812/ /pubmed/28509851 http://dx.doi.org/10.3390/s17051136 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Liang, Jinxing Zhang, Jing Zhou, Wenxiang Ueda, Toshitsugu Development of a Flow Injection Based High Frequency Dual Channel Quartz Crystal Microbalance |
title | Development of a Flow Injection Based High Frequency Dual Channel Quartz Crystal Microbalance |
title_full | Development of a Flow Injection Based High Frequency Dual Channel Quartz Crystal Microbalance |
title_fullStr | Development of a Flow Injection Based High Frequency Dual Channel Quartz Crystal Microbalance |
title_full_unstemmed | Development of a Flow Injection Based High Frequency Dual Channel Quartz Crystal Microbalance |
title_short | Development of a Flow Injection Based High Frequency Dual Channel Quartz Crystal Microbalance |
title_sort | development of a flow injection based high frequency dual channel quartz crystal microbalance |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470812/ https://www.ncbi.nlm.nih.gov/pubmed/28509851 http://dx.doi.org/10.3390/s17051136 |
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