Cargando…

New insights into redox homeostasis as a therapeutic target in B-cell malignancies

PURPOSE OF REVIEW: The goal of this review is to summarize recent advances in our understanding of the regulation of redox homeostasis and the subtype-specific role of antioxidant enzymes in B-cell-derived malignancies. Furthermore, it presents selected prooxidative therapeutic strategies against B-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Graczyk-Jarzynka, Agnieszka, Zagozdzon, Radoslaw, Muchowicz, Angelika, Siernicka, Marta, Juszczynski, Przemyslaw, Firczuk, Malgorzata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams And Wilkins 2017
Materias:	LYMPHOID BIOLOGY AND DISEASES: Edited by Ari Melnick
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470855/ https://www.ncbi.nlm.nih.gov/pubmed/28402987 http://dx.doi.org/10.1097/MOH.0000000000000351

Ejemplares similares

Role of the CARMA1/BCL10/MALT1 complex in lymphoid malignancies
por: Juilland, Mélanie, et al.
Publicado: (2016)

Targeting peroxiredoxin 1 impairs growth of breast cancer cells and potently sensitises these cells to prooxidant agents
por: Bajor, Malgorzata, et al.
Publicado: (2018)

Inhibition of autophagy sensitizes cancer cells to Photofrin-based photodynamic therapy
por: Domagala, Antoni, et al.
Publicado: (2018)

Targeting Negative and Positive Immune Checkpoints with Monoclonal Antibodies in Therapy of Cancer
por: Marhelava, Katsiaryna, et al.
Publicado: (2019)

Triple Combination of Ascorbate, Menadione and the Inhibition of Peroxiredoxin-1 Produces Synergistic Cytotoxic Effects in Triple-Negative Breast Cancer Cells
por: Bajor, Malgorzata, et al.
Publicado: (2020)

Inhibition of thioredoxin-dependent H(2)O(2) removal sensitizes malignant B-cells to pharmacological ascorbate
por: Graczyk-Jarzynka, Agnieszka, et al.
Publicado: (2018)

P1376: IDENTIFICATION OF SURFACEOME CHANGES IN CD19 CAR-T THERAPY-RESISTANT LYMPHOMA CELLS
por: Krawczyk, Marta, et al.
Publicado: (2023)

PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells
por: Bajor, Malgorzata, et al.
Publicado: (2022)

Immune Evasion as the Main Challenge for Immunotherapy of Cancer
por: Zagozdzon, Radoslaw, et al.
Publicado: (2022)

Targeting the thioredoxin system as a novel strategy against B‐cell acute lymphoblastic leukemia
por: Fidyt, Klaudyna, et al.
Publicado: (2019)

The Great War of Today: Modifications of CAR-T Cells to Effectively Combat Malignancies
por: Zhylko, Andriy, et al.
Publicado: (2020)

SBNO2 is a critical mediator of STAT3-driven hematological malignancies
por: Brandstoetter, Tania, et al.
Publicado: (2023)

JAK/STAT blockade reverses the malignant phenotype of Hodgkin and Reed-Sternberg cells
por: Fernández, Sara, et al.
Publicado: (2022)

A germinal center–associated microenvironmental signature reflects malignant phenotype and outcome of DLBCL
por: Miyawaki, Kohta, et al.
Publicado: (2022)

Comparing the value of mono- vs coculture for high-throughput compound screening in hematological malignancies
por: Herbst, Sophie A., et al.
Publicado: (2023)

Serine Biosynthesis Pathway Supports MYC–miR-494–EZH2 Feed-Forward Circuit Necessary to Maintain Metabolic and Epigenetic Reprogramming of Burkitt Lymphoma Cells
por: Białopiotrowicz, Emilia, et al.
Publicado: (2020)

NUDT15 variants confer high incidence of second malignancies in children with acute lymphoblastic leukemia
por: Yoshida, Masanori, et al.
Publicado: (2021)

Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies
por: Thomalla, D., et al.
Publicado: (2022)

Generation of a humanized afucosylated BAFF-R antibody with broad activity against human B-cell malignancies
por: Dong, Zhenyuan, et al.
Publicado: (2022)

Intraurethral co-transplantation of bone marrow mesenchymal stem cells and muscle-derived cells improves the urethral closure
por: Burdzinska, Anna, et al.
Publicado: (2018)

Incidence and time trends of second primary malignancies after non-Hodgkin lymphoma: a Swedish population-based study
por: Joelsson, Joel, et al.
Publicado: (2022)

Potent, p53-independent induction of NOXA sensitizes MLL-rearranged B-cell acute lymphoblastic leukemia cells to venetoclax
por: Fidyt, Klaudyna, et al.
Publicado: (2022)

Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy of Cancer
por: Wachowska, Małgorzata, et al.
Publicado: (2011)

A Specific CD44lo CD25lo Subpopulation of Regulatory T Cells Inhibits Anti-Leukemic Immune Response and Promotes the Progression in a Mouse Model of Chronic Lymphocytic Leukemia
por: Goral, Agnieszka, et al.
Publicado: (2022)

Regulatory T cells contribute to the immunosuppressive phenotype of neutrophils in a mouse model of chronic lymphocytic leukemia
por: Goral, Agnieszka, et al.
Publicado: (2023)

The Immune Landscape of Breast Cancer: Strategies for Overcoming Immunotherapy Resistance
por: Retecki, Kuba, et al.
Publicado: (2021)

The impact of prior malignancies on the development of second malignancies and survival in follicular lymphoma: A population‐based study
por: Dinnessen, Manette A.W., et al.
Publicado: (2020)

Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma
por: Trzeciecka, Anna, et al.
Publicado: (2015)

Exerkines and redox homeostasis
por: Félix-Soriano, Elisa, et al.
Publicado: (2023)

Selection of an optimal promoter for gene transfer in normal B cells
por: Winiarska, Magdalena, et al.
Publicado: (2017)

New insights into the links between hypoxia and iron homeostasis
por: Renassia, Cyril, et al.
Publicado: (2019)

PRDX-1 Supports the Survival and Antitumor Activity of Primary and CAR-Modified NK Cells under Oxidative Stress
por: Klopotowska, Marta, et al.
Publicado: (2022)

Second primary malignancies in chronic lymphocytic leukaemia: Skin, solid organ, haematological and Richter's syndrome
por: Shen, Yandong, et al.
Publicado: (2021)

FOXO1 promotes resistance of non-Hodgkin lymphomas to anti-CD20-based therapy
por: Pyrzynska, Beata, et al.
Publicado: (2018)

Malignant DFFB isoform switching promotes leukemia survival in relapse pediatric T‐cell acute lymphoblastic leukemia
por: Enlund, Sabina, et al.
Publicado: (2022)

SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma
por: Wrench, David, et al.
Publicado: (2011)

Poor neutralizing antibody responses in 106 patients with WM after vaccination against SARS-CoV-2: a prospective study
por: Gavriatopoulou, Maria, et al.
Publicado: (2021)

Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma
por: Silva, Ana, et al.
Publicado: (2021)

Oral ixazomib, lenalidomide, and dexamethasone for transplant-ineligible patients with newly diagnosed multiple myeloma
por: Facon, Thierry, et al.
Publicado: (2021)

Venetoclax sensitivity in multiple myeloma is associated with B-cell gene expression
por: Gupta, Vikas A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8voc6ec42jplh1gfo34v360anu