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Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A

The calcium-activated chloride channel TMEM16A is a member of a conserved protein family that comprises ion channels and lipid scramblases. Although the structure of the scramblase nhTMEM16 has defined the architecture of the family, it was unknown how a channel has adapted to cope with its distinct...

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Detalles Bibliográficos
Autores principales: Paulino, Cristina, Neldner, Yvonne, Lam, Andy KM, Kalienkova, Valeria, Brunner, Janine Denise, Schenck, Stephan, Dutzler, Raimund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470873/
https://www.ncbi.nlm.nih.gov/pubmed/28561733
http://dx.doi.org/10.7554/eLife.26232