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Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A
The calcium-activated chloride channel TMEM16A is a member of a conserved protein family that comprises ion channels and lipid scramblases. Although the structure of the scramblase nhTMEM16 has defined the architecture of the family, it was unknown how a channel has adapted to cope with its distinct...
Autores principales: | Paulino, Cristina, Neldner, Yvonne, Lam, Andy KM, Kalienkova, Valeria, Brunner, Janine Denise, Schenck, Stephan, Dutzler, Raimund |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470873/ https://www.ncbi.nlm.nih.gov/pubmed/28561733 http://dx.doi.org/10.7554/eLife.26232 |
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